Respiratory failure & ventilation
Effectiveness of Adaptive Support Ventilation in Facilitating Weaning from Mechanical Ventilation in Postoperative Patients
Pooled result · Time to extubationResult — go to the resultMean difference −68.30 hours 95% CI −115.50 to −21.09Authors' conclusion
ASV appears to facilitate a shorter time to extubation in postoperative cardiac surgery patients compared to conventional ventilation, suggesting benefits in accelerating the weaning process and reducing mechanical ventilation duration.
Study context
- Population
- Postoperative cardiac surgery patients weaning from mechanical ventilation
- Participants
- 1,027 patients · 11 RCTs
- Comparison
- Adaptive support ventilation (ASV) vs conventional ventilation
- Outcome
- Time to extubation
Methodological detailsrandom effects model, trial sequential analysis
- Random effects model
- Trial sequential analysis
Pooled result
As reported in the abstract
Mean difference
−68.30 hours
95% CI −115.50 to −21.09
ASV vs Conventional ventilation
mean difference −68.30 hours (95% CI −115.50 to −21.09)
Further pooled results
Early extubation rates
- ASV indicated improved early extubation rates
Reintubation rates, ICU and hospital LOS
- No significant differences
- Trial sequential analysis (TSA) results inconclusive (printed "inclusive")
Original publication
Effectiveness of Adaptive Support Ventilation in Facilitating Weaning from Mechanical Ventilation in Postoperative Patients. J Cardiothorac Vasc Anesth. Published 24 April 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →