Respiratory failure & ventilation
Effectiveness of diaphragmatic ultrasound as a predictor of successful weaning from mechanical ventilation
Authors' conclusion
DE-RSBI and DTF-RSBI are reliable predictors of MV weaning, outperforming RSBI alone.
Study context
- Population
- Adults mechanically ventilated >48 hours undergoing spontaneous breathing trials (SBT), ICU of Menoufia University Hospitals
- Participants
- 50 participants
- Comparison
- Diaphragmatic excursion RSBI (DE-RSBI) and diaphragm thickening fraction RSBI (DTF-RSBI) vs conventional Rapid Shallow Breathing Index (RSBI) for predicting weaning success
- Outcome
- Weaning success (spontaneous breathing for >48 hours post-extubation)
Methodological detailsobservational, single-centre
- Observational
- Single-centre
Performance
As reported in the abstract
Prediction of weaning success
| Test or model | Cut-off | AUC | Sensitivity | Specificity |
|---|---|---|---|---|
| DE-RSBI | ≥1.685 | 0.851 | 80% | 85% |
DE-RSBI
Cut-off≥1.685
AUC0.851
Sensitivity80%
Specificity85%
Further findings
Odds of weaning failure
| OR | P value | |
|---|---|---|
| DE-RSBI >1.56 | 12 | P = 0.004 |
| DTF-RSBI >62.33 | 8.04 | P = 0.008 |
| RSBI | 4.84 | P = 0.04 |
Correlation with ICU mortality and mechanical ventilation (MV) duration
- DE-RSBI and DTF-RSBI correlated with ICU mortality
- P < 0.001
- DE-RSBI and DTF-RSBI correlated with MV duration
- P ≤ 0.001
Original publication
Effectiveness of diaphragmatic ultrasound as a predictor of successful weaning from mechanical ventilation. J Clin Monit Comput. Published 14 July 2025. doi:10.
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