Respiratory failure & ventilation
Predictive value of diaphragmatic ultrasound for weaning outcomes in mechanically ventilated patients with acute exacerbation of chronic obstructive pulmonary disease: a systematic review and meta-analysis
Authors' conclusion
Diaphragm ultrasound, particularly DE, may provide useful prognostic information for weaning outcomes in mechanically ventilated patients with AECOPD, while D-RSBI may help identify patients at high risk of weaning failure.
Study context
- Population
- Mechanically ventilated patients with acute exacerbation of COPD (acute exacerbation of chronic obstructive pulmonary disease (AECOPD))
- Participants
- 2,000 participants · 23 studies
- Comparison
- Diaphragmatic ultrasound parameters for predicting weaning outcome
- Outcome
- Diagnostic accuracy of diaphragmatic ultrasound for predicting weaning outcomes
Methodological detailsbivariate random-effects models, QUADAS-2 quality appraisal
- Bivariate random-effects models
- QUADAS-2 quality appraisal
Pooled result
As reported in the abstract
Prediction of weaning outcome
| Group | Studies | Pooled sensitivity | Specificity | AUC | Sensitivity |
|---|---|---|---|---|---|
| Diaphragmatic excursion (DE) | 16 | 0.85 | 0.85 | 0.92 | |
| Diaphragm thickening fraction (DTF) | 13 | 0.77 | 0.88 | 0.84 | |
| Diaphragmatic rapid shallow breathing index (D-RSBI) | 8 | 0.88 | 0.85 | 0.74 | |
| Diaphragmatic contraction velocity (DCV) | 4 | 0.70 |
Studies
Diaphragmatic excursion (DE)16
Diaphragm thickening fraction (DTF)13
Diaphragmatic rapid shallow breathing index (D-RSBI)8
Diaphragmatic contraction velocity (DCV)4
Pooled sensitivity
Diaphragmatic excursion (DE)0.85
Diaphragm thickening fraction (DTF)— not stated in the abstract
Diaphragmatic rapid shallow breathing index (D-RSBI)— not stated in the abstract
Diaphragmatic contraction velocity (DCV)— not stated in the abstract
Specificity
Diaphragmatic excursion (DE)0.85
Diaphragm thickening fraction (DTF)0.77
Diaphragmatic rapid shallow breathing index (D-RSBI)0.88
Diaphragmatic contraction velocity (DCV)— not stated in the abstract
AUC
Diaphragmatic excursion (DE)0.92
Diaphragm thickening fraction (DTF)0.88
Diaphragmatic rapid shallow breathing index (D-RSBI)0.85
Diaphragmatic contraction velocity (DCV)0.70
Sensitivity
Diaphragmatic excursion (DE)— not stated in the abstract
Diaphragm thickening fraction (DTF)0.84
Diaphragmatic rapid shallow breathing index (D-RSBI)0.74
Diaphragmatic contraction velocity (DCV)— not stated in the abstract
Original publication
Predictive value of diaphragmatic ultrasound for weaning outcomes in mechanically ventilated patients with acute exacerbation of chronic obstructive pulmonary disease: a systematic review and meta-analysis. Crit Care. Published 8 August 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →