Respiratory failure & ventilation

The ratio of parasternal intercostal muscle-thickening fraction-to-diaphragm thickening fraction for predicting weaning failure

J Crit CarePublished Diagnostic accuracy study

Authors' conclusion

The TFic/TFdi ratio predicted weaning failure with high accuracy and outperformed the D-RSBI.

Study context

Population
Mechanically ventilated patients undergoing weaning, 7/2022–5/2023114 [70.8%] weaned
Participants
161 participants
Comparison
TFic/TFdi ratio vs D-RSBI for predicting weaning failure
Outcome
Accuracy (AUROC) for predicting weaning failure
Methodological detailsprospective, consecutive enrolment
  • Prospective
  • Consecutive enrolment

Performance

As reported in the abstract

Weaning failure prediction
Test or modelAUROC
TFic/TFdi ratio0.887 (95% CI: 0.821-0.953)
D-RSBI0.875 (95% CI: 0.807-0.944)

AUROC

TFic/TFdi ratio0.887 (95% CI: 0.821-0.953)
D-RSBI0.875 (95% CI: 0.807-0.944)

Original publication

The ratio of parasternal intercostal muscle-thickening fraction-to-diaphragm thickening fraction for predicting weaning failure. J Crit Care. Published 22 June 2024. doi:10.1016/j.jcrc.2024.154847

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