Pediatric anesthesia & critical care
The effects of dexmedetomidine on intraoperative neurophysiologic monitoring modalities during corrective scoliosis surgery in pediatric patients: A systematic review
Study context
- Population
- Pediatric patients with scoliosis undergoing spinal fusion surgery
- Participants
- 5 included articles
- Comparison
- Dexmedetomidine vs Standardized anesthesia
- Outcome
- MEP amplitude or SSEP latency and amplitude; dose effects of dexmedetomidine
Methodological detailsnarrative synthesis without meta-analysis
- Narrative synthesis without meta-analysis
Pooled result
As reported in the abstract
MEP loss
- Articles with lowest risk of bias: dexmedetomidine associated with motor evoked potentials (MEP) loss; higher doses increased risk
- Articles reporting no association between dexmedetomidine and MEP loss had higher risk of bias
- Substantial heterogeneity in risk of bias; results summarized without meta-analysis
Original publication
The effects of dexmedetomidine on intraoperative neurophysiologic monitoring modalities during corrective scoliosis surgery in pediatric patients: A systematic review. Paediatr Anaesth. Published 5 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →