Cardiothoracic & vascular anesthesia
Dexmedetomidine and magnesium sulfate in preventing junctional ectopic tachycardia after pediatric cardiac surgery
Authors' conclusion
Dexmedetomidine alone or combined with MgSO4 had a therapeutic role in the prevention of JET in children after congenital heart surgery.
Study context
- Population
- Children under 5 years, weighing more than 5 kg, scheduled for corrective acyanotic cardiac surgery
- Participants
- 120 participants
- Comparison
- Dexmedetomidine plus MgSO4 or dexmedetomidine alone vs control
- Primary endpoint
- Detection of JET incidence
Methodological detailsthree-arm
- Three-arm
Primary result
As reported in the abstract
JET incidence
- Junctional ectopic tachycardia (JET) incidence significantly reduced in Group MD and Group D vs Group C
- Group MD and Group D vs Group C: P = 0.007
Secondary outcomes
| Outcome | P value |
|---|---|
| Ionized Mg (rewarming and ICU)Group MD vs Groups D and C · significantly higher in Group MD | P < 0.001 |
| Hemodynamic profile and predictive indexes, incl. extubation time, PCCU and hospital stayGroup MD vs Groups D and C · significantly better in Group MD | P < 0.001 |
Hemodynamic profile and predictive indexes, incl. extubation time, PCCU and hospital stay
- Better hemodynamic profile in Group MD vs Group D and Group C throughout surgery and in the ICU
Original publication
Dexmedetomidine and magnesium sulfate in preventing junctional ectopic tachycardia after pediatric cardiac surgery. Paediatr Anaesth. Published 25 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →