Neuroanaesthesia & neurocritical care

Effects of goal-directed fluid management guided by a non-invasive device on the incidence of postoperative complications in neurosurgery: a pilot and feasibility randomized controlled trial

Perioper Med (Lond)Published Randomised controlled trial

Authors' conclusion

The rate of postoperative complications was comparable between groups.

Study context

Population
Adults scheduled for elective neurosurgeryenrollment target
Participants
34 adults
Comparison
GDT guided by non-invasive hemodynamic monitoring vs standard therapy
Primary endpoint
Safety and feasibility of GDHT (feasibility criteria; adverse events)
Methodological detailspilot and feasibility, single-centre
  • Pilot and feasibility
  • Single-centre

Primary result

As reported in the abstract

Feasibility and safety
Unsatisfactory brain tissue relaxation after surgery or brain edema requiring therapy (during surgery or 24 h after), either group
0

Further findings

Major postoperative complications

P = 0.105

Safety

Events

OutcomeGDHTControl
Unsatisfactory brain tissue relaxation or brain edema requiring therapy · during surgery or 24 h after surgery00

Original publication

Effects of goal-directed fluid management guided by a non-invasive device on the incidence of postoperative complications in neurosurgery: a pilot and feasibility randomized controlled trial. Perioper Med (Lond). Published 5 July 2023. doi:10.1186/s13741-023-00321-3

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