Effects of manual and syringe pump induction of total intravenous anaesthesia on propofol waste: a single-centre retrospective analysis
Main finding · Total propofol waste per surgeryResult — go to the resultLess waste 32.8%Authors' conclusion
Syringe pump induction reduced propofol waste during TIVA, regardless of patient characteristics.
Study context
- Population
- Procedures under total intravenous anaesthesia (TIVA) with propofol
- Participants
- 331 procedures
- Exposure
- Syringe pump vs manual induction of TIVA
- Outcome
- Total propofol waste per surgery
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Less waste
32.8%
P < 0.001
Observational data: associations, not effects.
Secondary outcomes
| Outcome | Less waste | P value |
|---|---|---|
| Propofol waste, procedures lasting 20-40 min (subgroup) | 46.9% | P < 0.001 |
| Propofol waste, procedures lasting 100-120 min (subgroup) | 48.8% | P = 0.003 |
| Propofol waste, patients with active substance use (subgroup) | 48.7% | P = 0.0015 |
| Propofol waste, patients without substance use (subgroup) | 22.7% | P = 0.0045 |
Propofol waste by sex, age, weight, BMI, American Society of Anesthesiologists (ASA) physical status (subgroup)
- Amount of waste not affected by biological sex, age, weight, BMI, or ASA physical status
- Syringe pump induction consistently associated with less waste, except in patients with obesity
Propofol waste, active substance use vs none (subgroup)
- Active substance use: more waste with manual induction
- 27.6%
- P=0.031; not with syringe pump induction
Original publication
Effects of manual and syringe pump induction of total intravenous anaesthesia on propofol waste: a single-centre retrospective analysis. Br J Anaesth. Published 29 October 2024. doi:10.
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