Effects of preoperative binaural beats on the propofol dose for induction of general anesthesia: a randomized controlled trial
Primary resultResult — go to the resultDifference in means −18 mg 95% CI −32 to −5Authors' conclusion
Binaural beats with a frequency of 1 Hz modestly reduced the propofol dose for the induction of general anesthesia, but we observed no significant differences in the processed frontal electroencephalograms and preoperative anxiety levels.
Study context
- Population
- Patients scheduled for elective surgery under GA
- Participants
- 34 vs 35
- Comparison
- Binaural-beats vs Control
- Binaural-beatsn = 34
- Controln = 35reference
- Primary endpoint
- Propofol dose for loss of response to verbal commands ("open your eyes"); propofol 10 mg every 15 sec
Primary result
As reported in the abstract
Difference in means
−18 mg
95% CI −32 to −5
P = 0.009
By group
Binaural-beats vs Control
difference in means −18 mg (95% CI −32 to −5); P = 0.009
Further findings
Processed frontal EEG bands
- No significant difference in delta band
- P = 0.63
- No significant difference in theta band
- P = 0.28
- No significant difference in alpha band
- P = 0.24
- No significant difference in beta band
- P = 0.85
Anxiety scores
- No significant difference
- P = 0.50
Original publication
Effects of preoperative binaural beats on the propofol dose for induction of general anesthesia: a randomized controlled trial. Can J Anaesth. Published 25 June 2025. doi:10.
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