Perioperative medicine & outcomes

Effects of Peripheral Nerve Block on Perioperative Recovery following Major Thoracic and Abdominal Surgery: A Retrospective Cohort Study With Propensity-score Matching

Ann SurgPublished Retrospective cohort study

Main finding · Length of hospital stay after surgeryResult — go to the resultHazard ratio 1.15 95% CI 1.02–1.29

Authors' conclusion

The use of PNB was associated with shortened length of hospital stay and reduced major complications in older patients after major non-cardiac thoracic and abdominal surgery, possibly due to improved analgesia.

Study context

Population
Patients aged ≥65 years undergoing major (≥2 hours) non-cardiac thoracic and abdominal surgery under GA1,174 matched
Participants
1,915 patients
Exposure
Peripheral nerve block (PNB) vs no PNB during GA
  • PNBn = 587
  • Without PNBn = 587reference
Outcome
Length of hospital stay
Methodological detailspropensity score matching
  • Propensity score matching

Main finding

Length of hospital stay after surgery

Hazard ratio

1.15

95% CI 1.02–1.29

P = 0.012

By group

PNB vs Without PNB
HR 1.15 (95% CI 1.02–1.29); P = 0.012

As reported in the abstract

Observational data: associations, not effects.

Secondary outcomes

OutcomeRR (95% CI)P value
Supplemental analgesia within 72 h0.70 (0.59–0.84)P < 0.001

Safety

OutcomeRR (95% CI)P value
Major complications during hospital stay0.41 (0.30–0.58)P < 0.001

Original publication

Effects of Peripheral Nerve Block on Perioperative Recovery following Major Thoracic and Abdominal Surgery: A Retrospective Cohort Study With Propensity-score Matching. Ann Surg. Published 5 February 2025. doi:10.1097/sla.0000000000006652

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