Cardiothoracic & vascular anesthesia
Efficacy of Hemoadsorption in Cardiac Surgery with Cardiopulmonary Bypass: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Pooled result · AKI incidence, RRT requirement and mortality (primary outcomes)Result — go to the resultRelative risk 0.75 95% CI 0.59–0.96Authors' conclusion
Intraoperative HA during CPB reduces the risk of AKI but does not significantly affect other major postoperative outcomes.
Study context
- Population
- Patients undergoing cardiac surgery with cardiopulmonary bypass (CPB)
- Participants
- 1,133 patients · 16 randomized controlled trials (RCTs)
- Comparison
- CPB with vs without intraoperative hemoadsorption
- Outcome
- AKI incidence, RRT requirement and mortality
Methodological detailsPRISMA guidelines
- PRISMA guidelines
Pooled result
As reported in the abstract
AKI incidence, RRT requirement and mortality (primary outcomes)
Relative risk
0.75
95% CI 0.59–0.96
P = 0.020
HA vs No HA
RR 0.75 (95% CI 0.59–0.96); P = 0.020
- RRT requirement: no significant difference
- RR 0.64; p = 0.58
- Mortality: no significant difference
- RR 0.96; p = 0.861
Further pooled results
ICU/hospital LOS, postoperative delirium, stroke, sepsis, reoperation
- No significant effects for secondary outcomes
Original publication
Efficacy of Hemoadsorption in Cardiac Surgery with Cardiopulmonary Bypass: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J Cardiothorac Vasc Anesth. Published 10 January 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →