Cardiothoracic & vascular anesthesia
Intraoperative Hemoadsorption and Acute Kidney Injury in Cardiac Surgery: Systematic Review and Meta-analysis
Pooled result · AKI incidenceResult — go to the resultRelative risk 0.66 95% CI 0.49–0.87Authors' conclusion
Intraoperative HA may be associated with a lower AKI incidence in observational studies, but randomized data do not confirm a causal benefit.
Study context
- Population
- Patients undergoing cardiovascular surgery with cardiopulmonary bypass (CPB)
- Participants
- 1,797 patients · 17 studies · 7 randomized controlled trials (RCTs)
- Comparison
- Intraoperative hemoadsorption (HA) vs standard surgical treatment
- HAn = 826
- Outcome
- AKI incidence
Methodological detailsrandom-effects model
- Random-effects model
Pooled result
As reported in the abstract
Relative risk
0.66
95% CI 0.49–0.87
P = 0.008
HA vs Standard surgical treatment
RR 0.66 (95% CI 0.49–0.87); P = 0.008
Further pooled results
- Need for RRT did not differ significantly between groups
- RR, 0.83; 95% CI, 0.63-1.11; p = 0.19
Original publication
Intraoperative Hemoadsorption and Acute Kidney Injury in Cardiac Surgery: Systematic Review and Meta-analysis. J Cardiothorac Vasc Anesth. Published 4 December 2025. doi:10.
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