Cardiothoracic & vascular anesthesia

Efficacy of Superficial versus Deep Parasternal Intercostal Plane Blocks in Cardiac Surgery: A Systematic Review and Meta-Analysis

J Cardiothorac Vasc AnesthPublished Systematic review and meta-analysis of randomised and observational studies

Pooled resultResult — go to the resultMean difference −1.23 95% CI −2.51 to 0.05

Authors' conclusion

S-PIP and D-PIP blocks provide comparable postoperative analgesic efficacy in patients undergoing cardiac surgery.

Study context

Population
Patients undergoing cardiac surgery7 randomized controlled trials (RCTs), 1 observational study
Participants
510 patients
Comparison
Superficial parasternal intercostal plane (S-PIP) vs deep parasternal intercostal plane (D-PIP) block
Outcome
Postoperative opioid consumption (morphine milligram equivalent (MME))
Follow-up
24 hours

Pooled result

As reported in the abstract

Mean difference

−1.23

95% CI −2.51 to 0.05

P = 0.061

S-PIP vs D-PIP
mean difference −1.23 (95% CI −2.51 to 0.05); P = 0.061

Further pooled results

Pain scores, time to rescue analgesics, extubation time, intensive care unit (ICU) length of stay (LOS)

No significant differences between the 2 techniques

Safety

Postoperative nausea and vomiting (PONV) incidence

No significant difference between the 2 techniques

Original publication

Efficacy of Superficial versus Deep Parasternal Intercostal Plane Blocks in Cardiac Surgery: A Systematic Review and Meta-Analysis. J Cardiothorac Vasc Anesth. Published 29 May 2025. doi:10.1053/j.jvca.2025.05.053

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