Cardiothoracic & vascular anesthesia
Efficacy of Surgeon-Administered Regional Anesthesia in Cardiac Surgery: A Double-Blinded, 2-Center, Randomized, Placebo-Controlled Trial
Authors' conclusion
In this double-blind, randomized trial, surgeon-administered regional anesthesia did not reduce opioid consumption or provide additional clinical benefits following median sternotomy.
Study context
- Population
- Patients undergoing non-emergent CABG via median sternotomy, 2 Danish university hospitals100 completed and analysed
- Participants
- 113 patients
- Comparison
- Active intervention vs Placebo
- Primary endpoint
- Total opioid consumption
- Follow-up
- First 24 postoperative hours
Methodological detailsdouble-blinded, placebo-controlled, 2-center
- Double-blinded
- Placebo-controlled
- 2-center
Primary result
As reported in the abstract
Oral morphine equivalents · 24 h
P = 0.649
Secondary outcomes
Postoperative pain, recovery, respiratory impact, chronic opioid use
- No significant differences
Safety
Safety endpoints
- No significant differences
Original publication
Efficacy of Surgeon-Administered Regional Anesthesia in Cardiac Surgery: A Double-Blinded, 2-Center, Randomized, Placebo-Controlled Trial. J Cardiothorac Vasc Anesth. Published 27 March 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →