Cardiothoracic & vascular anesthesia
Efficacy of preoperative single-dose dexamethasone in preventing postoperative pulmonary complications following minimally invasive esophagectomy: a retrospective propensity score-matched study
Authors' conclusion
Preoperative DXM before induction of anesthesia did not reduce overall PPC development after MIE. Nevertheless, the occurrence of early respiratory failure and the incidence of re-intubation during hospitalization were decreased.
Study context
- Population
- Patients who underwent total minimally invasive esophagectomy (MIE) with two-field lymph node dissection, February 2018 to February 2023366 matched
- Participants
- 659 patients
- Exposure
- Preoperative single-dose dexamethasone (DXM) before induction of GA vs no DXM
- DXMn = 183
- Controln = 183reference
- Outcome
- Incidence of postoperative pulmonary complications (PPCs)
- Follow-up
- By day 7 after surgery
Methodological detailspropensity-score matched
- Propensity-score matched
Main finding
As reported in the abstract
P = 0.198
Observational data: associations, not effects.
Further findings
Respiratory failure · significantly lower in the DXM group
P = 0.019
Re-intubation during hospital stay
P = 0.019
Original publication
Efficacy of preoperative single-dose dexamethasone in preventing postoperative pulmonary complications following minimally invasive esophagectomy: a retrospective propensity score-matched study. Perioper Med (Lond). Published 28 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →