Cardiac arrest & resuscitation

Eighteen‐year trends in the rates of intra‐operative cardiac arrest and associated mortality at a public university hospital in Brazil*

AnaesthesiaPublished Retrospective observational study

Authors' conclusion

We have shown an important reduction in intra-operative cardiac arrest and associated 30-day mortality over an 18-year period.

Study context

Population
Anaesthetics at a public quaternary university teaching hospital in Brazil, 1 January 2005 to 31 December 2022
Participants
154,178 cases
Exposure
2005-2010 vs 2017-2022
Outcome
Intra-operative cardiac arrest and associated 30-day mortality (per 10,000 anaesthetics)
Methodological detailssingle-centre, quaternary teaching hospital, multivariable logistic regression
  • Single-centre
  • Quaternary teaching hospital
  • Multivariable logistic regression

Main finding

As reported in the abstract

Intra-operative cardiac arrest and associated 30-day mortality per 10,000 anaesthetics
Overall intra-operative cardiac arrest (n = 297), per 10,000 anaesthetics
19.3 (95%CI 16.6-21.9)
Overall associated 30-day mortality (n = 248), per 10,000 anaesthetics
16.1 (95% CI 13.9-18.3)
Cardiac arrest, 2005-2010, per 10,000 anaesthetics
26.3 (95%CI 21.0-31.6)
Cardiac arrest, 2017-2022, per 10,000 anaesthetics
15.4 (95%CI 12.0-18.7)
30-day mortality, 2005-2010, per 10,000 anaesthetics
23.4 (95%CI 18.8-28.1)
30-day mortality, 2017-2022, per 10,000 anaesthetics
13.7 (95%CI 10.8-16.7)

Observational data: associations, not effects.

Further findings

Factors associated with intra-operative cardiac arrest

Children aged < 1 year, aOR
3.51 (1.87-6.57) (95%CI)
ASA physical status 3-5, aOR
13.85 (8.86-21.65) (95%CI)
Emergency surgery, aOR
10.06 (7.85-12.89) (95%CI)
GA, aOR
8.79 (4.60-19.64) (95%CI)
Procedure involving multiple specialities, aOR
9.13 (4.24-19.64) (95%CI)
Cardiac surgery, aOR
7.69 (5.05-11.71) (95%CI)
Vascular surgery, aOR
6.21 (4.05-9.51) (95%CI)
Gastrointestinal surgery, aOR
2.98 (1.91-4.65) (95%CI)
  • Multivariable logistic regression

Original publication

Eighteen‐year trends in the rates of intra‐operative cardiac arrest and associated mortality at a public university hospital in Brazil*. Anaesthesia. Published 13 October 2024. doi:10.1111/anae.16450

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