Respiratory failure & ventilation
Elastic power, a novel predictor of the severity and prognosis of ARDS
Authors' conclusion
EP can be used to predict the severity of ARDS, and Cst-EP is associated with mortality during controlled mechanical ventilation in ARDS.
Study context
- Population
- ARDS patients under invasive mechanical ventilation for at least 48 h (MIMIC-III database)
- Exposure
- High vs low Cst-EP; Elastic power (EP) as predictor of ARDS severity
- Outcome
- Severity of ARDS (EP) and 28-day prognosis (Cst-EP)
- Follow-up
- 28 days
Methodological detailsMIMIC-III database
- MIMIC-III database
Main finding
As reported in the abstract
Estimate (95% CI)P value
EPindependently associated with ARDS severity
OR 1.301(1.190–1.423)
P < 0.001Cst-EPrisk of death
HR 1.169 per 100 J/min × cmH2O/ml × 10-3(1.093–1.250)
P < 0.001Per 100 J/min × cmH2O/ml × 10-3, as printed
- EP optimal cut-off for ARDS severity
- 14.6 J/min
Observational data: associations, not effects.
Original publication
Elastic power, a novel predictor of the severity and prognosis of ARDS. J Crit Care. Published 20 July 2023. doi:10.
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