Respiratory failure & ventilation
Electrical impedance tomography-derived flow index during spontaneous breathing trial stratifies the risk of reintubation within 48 h after extubation
Authors' conclusion
EFI measured during SBT was strongly associated with SBT outcome and showed an exploratory association with reintubation within 48 h after extubation.
Study context
- Population
- Adults receiving invasive mechanical ventilation for at least 48 h undergoing a standardized 30-min pressure support spontaneous breathing trial (SBT) with continuous electrical impedance tomography (EIT) monitoring107 extubated
- Participants
- 150 adults
- Exposure
- EIT-derived flow index (EFI) during SBT for SBT outcome and reintubation within 48 h
- Outcome
- SBT outcome:
- EFI discrimination for SBT failure
- ROC analysis
Methodological detailsmulticentre, prespecified key secondary endpoint
- Multicentre
- Prespecified key secondary endpoint
Main finding
As reported in the abstract
EFI discrimination for SBT outcome
AUC of EFI for SBT outcome (excellent discrimination)
0.980
Observational data: associations, not effects.
Secondary outcomes
Reintubation within 48 h after extubation
- Reintubation within 48 h among extubated patients
- 7 of 107
- EFI < 1.333 had significantly lower 48-h freedom from reintubation than EFI ≥ 1.333; all reintubations in EFI < 1.333
- EFI, RSBI, MIP and P0.1 each associated with reintubation in univariable Cox analyses
- Multivariable model not pursued (severe multicollinearity, very small number of events)
Original publication
Electrical impedance tomography-derived flow index during spontaneous breathing trial stratifies the risk of reintubation within 48 h after extubation. Crit Care. Published 31 May 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →