Respiratory failure & ventilation
Ventilation distribution during spontaneous breathing trials predicts liberation from mechanical ventilation: the VISION study
Authors' conclusion
During SBT, a large ventral-to-dorsal difference in ventilation indicated by EIT may help to rapidly identify patients at risk of liberation failure.
Study context
- Population
- Mechanically ventilated patients undergoing an Spontaneous Breathing Trial (SBT), monitored with electrical impedance tomography (EIT)analysed
- Participants
- 98 participants
- Comparison
- Liberation success vs Failure
- Liberation successn = 40
- Outcome
- Prediction of liberation from mechanical ventilation (MV) by ventral-to-dorsal ventilation difference (%) on EIT during SBT
Methodological detailstraining and validation cohorts
- Training and validation cohorts
Performance
As reported in the abstract
Prediction of liberation failure by EIT ventral-to-dorsal ventilation difference · 5 min of SBT
| Test or model | Sensitivity | Specificity | PPV |
|---|---|---|---|
| Absolute difference at 5 min of SBT > 20% | 71% | 78% | 81% |
Absolute difference at 5 min of SBT > 20%
Sensitivity71%
Specificity78%
PPV81%
- Absolute ventral-to-dorsal difference consistently smaller in liberation success vs all subgroups of failure, from first minutes to entire SBT
- P < 0.0001
Further findings
SBT outcome and reintubation
- Passed SBT
- 85 (87%)
- Rapid liberation success
- 40
- Extubated patients requiring reintubation
- 13.5%
Original publication
Ventilation distribution during spontaneous breathing trials predicts liberation from mechanical ventilation: the VISION study. Crit Care. Published 7 January 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →