Respiratory failure & ventilation

Occurrence of pendelluft during ventilator weaning with T piece correlated with increased mortality in difficult-to-wean patients

J Intensive CarePublished Retrospective observational study

Authors' conclusion

Pendelluft occurred in 70.4% of difficult-to-wean patients undergoing T piece spontaneous breathing. Pendelluft was associated with worse clinical outcomes, including prolonged mechanical ventilation and increased mortality in this population.

Study context

Population
Difficult-to-wean patients undergoing spontaneous T piece breathing with electrical impedance tomography (EIT) monitoring
Participants
108 patients
Exposure
Pendelluft vs no pendelluft during T piece spontaneous breathing trial (SBT)
  • Pendelluftn = 72
Outcome
28-day mortality
Follow-up
Day 28

Main finding

As reported in the abstract

P = 0.035

Presence of pendellfut independently associated with increased mortality at day 28
OR 10.50 (95% CI 1.21-90.99, p = 0.033)

Observational data: associations, not effects.

Further findings

Mechanical ventilation duration

P = 0.041

Ventilator-free days · day 28

P = 0.043

Pendelluft occurrence
70.4% · 72

Overall mortality by day 28

Deaths by day 28, all patients
16 (14.8%)

Original publication

Occurrence of pendelluft during ventilator weaning with T piece correlated with increased mortality in difficult-to-wean patients. J Intensive Care. Published 24 June 2024. doi:10.1186/s40560-024-00737-z

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