Perioperative medicine & outcomes
Enhanced Recovery After Surgery Program and Opioid Consumption in Pulmonary Resection Surgery: A Retrospective Observational Study
Main finding · Total opioid consumption (MME)Result — go to the resultMedian difference −143 mg 95% CI −154 to −132Authors' conclusion
Patients who underwent pulmonary resection under the ERAS program consumed fewer opioids than those who received conventional management while maintaining no significant differences in clinical outcomes.
Study context
- Population
- Patients undergoing pulmonary resection surgery, August 2019–December 2020included in the analysis
- Participants
- 2,120 patients
- Exposure
- Enhanced recovery after surgery (ERAS) program vs conventional treatment
- ERASn = 260
- Conventionaln = 1,860reference
- Outcome
- Total opioid consumption from surgery to discharge
Methodological detailsstabilized inverse probability of treatment weighting, single institution
- Stabilized inverse probability of treatment weighting
- Single institution
Main finding
Total opioid consumption (MME) · after surgery until discharge
Median difference
−143 mg
95% CI −154 to −132
P < 0.001
By group
ERAS vs Conventional
median difference −143 mg (95% CI −154 to −132); P < 0.001
As reported in the abstract
Observational data: associations, not effects.
Secondary outcomes
| Outcome | ERAS | Conventional | OR (95% CI) | P value | |
|---|---|---|---|---|---|
| Discharged without opioid prescription | 60% | 18% | 7.0 (5.3–9.3) | P < 0.001 | |
| 0.10.31310Odds ratio (log scale) |
| Outcome | ERAS | Conventional | Mean difference (95% CI) | P value | |
|---|---|---|---|---|---|
| Average pain intensity score during exertion · operation day | 3.0 ± 1.7 | 3.5 ± 1.8 | −0.5 (−0.8 to −0.3) | P < 0.001 | |
| Highest pain intensity score during exertion · operation day | 5.5 ± 2.1 | 6.4 ± 1.7 | −0.8 (−1.0 to −0.5) | P < 0.001 | |
| −1.5−1−0.500.5Difference (linear scale) |
Intensive care unit (ICU) LOS, hospital stay, Clavien-Dindo grade
- No significant differences
Original publication
Enhanced Recovery After Surgery Program and Opioid Consumption in Pulmonary Resection Surgery: A Retrospective Observational Study. Anesth Analg. Published 8 February 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →