Respiratory failure & ventilation
Epidemiological trends of mechanically ventilated acute respiratory distress syndrome in the twenty-first century: a nationwide, population-based retrospective study
Authors' conclusion
MV-ARDS incidence has stabilized in recent years, with mortality showing a declining trend. ARDS-related costs have increased nearly fourfold.
Study context
- Population
- All hospitalizations for mechanically ventilated acute respiratory distress syndrome (ARDS) (mechanically ventilated ARDS (MV-ARDS)) in Spanish hospitals, 2000–2022records analysed
- Participants
- 93,192 hospitalizations
- Outcome
- MV-ARDS incidence per 100,000 population/year, hospital mortality rate and mean cost per patient
Methodological detailsadministrative database (Minimum Basic Data Set (MBDS))
- Administrative database (MBDS)
Main finding
As reported in the abstract
2000–2022
MV-ARDS incidence range (/100,000 population-years), peak in 2021
2.96 to 20.14
Hospital mortality range, declining trend
38.0 and 55.0%
Peak cost per patient (2011), then stabilizing ~€30,000-€40,000
€42,812
Observational data: associations, not effects.
Further findings
Effect of COVID-19 pandemic
- Hospital stay lengthened during the pandemic
- P < 0.001
- Hospital mortality decreased during the pandemic
- P < 0.001
- Increased proportion of patients with obesity and DM, with fungal or viral etiologies
Original publication
Epidemiological trends of mechanically ventilated acute respiratory distress syndrome in the twenty-first century: a nationwide, population-based retrospective study. J Intensive Care. Published 17 February 2025. doi:10.
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