Respiratory failure & ventilation
Outcomes and predictors of mortality in patients with severe COVID-19 and chronic obstructive pulmonary disease (COPD) admitted to ICU: A multicenter study
Main finding · 90-day mortality predictors in COPD (95% with ARDS due to COVID-19)Result — go to the resultHazard ratio 0.54 95% CI 0.31–0.95Authors' conclusion
In COPD patients with ARDS due to COVID-19, the use of HFNC was associated with a better prognosis.
Study context
- Population
- Patients hospitalized with COVID-19 in 55 Spanish intensive care units (ICUs)
- Participants
- 6,512 patients · 55 Spanish ICUs
- Exposure
- COPD vs other chronic respiratory diseases (CRD) vs No CRD; within COPD, predictors of 90-day mortality
- COPDn = 328
- CRDn = 547
- No CRDn = 5,124reference
- Outcome
- Clinical predictors for 90-day mortality, focusing on the COPD group
- Follow-up
- 90 days
Methodological details55 Spanish ICUs, propensity score matching
- 55 Spanish ICUs
- Propensity score matching
Main finding
As reported in the abstract
90-day mortality predictors in COPD (95% with Acute Respiratory Distress Syndrome (ARDS) due to COVID-19)
Hazard ratio
0.54
95% CI 0.31–0.95
HFNC
HR 0.54 (95% CI 0.31–0.95)
Observational data: associations, not effects.
Further findings
- Mortality by respiratory comorbidity — COPD
- 50%
Mortality by respiratory comorbidity
- 33% mortality in those with other CRD and those without respiratory comorbidities (No CRD)
Original publication
Outcomes and predictors of mortality in patients with severe COVID-19 and COPD admitted to ICU: A multicenter study. Anaesth Crit Care Pain Med. Published 22 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →