Equal mixture of 2% lidocaine with adrenaline and 0.5% bupivacaine 20 mL provided faster onset of complete conduction blockade during ultrasound-guided supraclavicular brachial plexus block than 20 mL of 0.5% bupivacaine alone: a randomized double-blinded clinical trial
Authors' conclusion
At 20 mL LA volume, equal mixture of lidocaine and bupivacaine provided significantly faster onset of CCB compared with bupivacaine alone and longer duration of postoperative analgesia compared with lidocaine alone but shorter than bupivacaine alone during low-volume USG-SCBPB.
Study context
- Population
- Patients receiving ultrasound-guided (USG) supraclavicular brachial plexus block
- Participants
- 63 patients
- Comparison
- L vs B vs LB
- Primary endpoint
- Onset of complete conduction blockade (CCB) vs bupivacaine alone; duration of analgesia vs lidocaine alone
Methodological detailsdouble-blinded
- Double-blinded
Primary result
As reported in the abstract
Time to CCB (patients attaining CCB)
P > 0.05
Further findings
Proportion attaining complete conduction block (TCS=16/16) · up to 40 min — B vs L and LB · significantly lower in B
P = 0.0001
Duration of postoperative analgesia
Original publication
Equal mixture of 2% lidocaine with adrenaline and 0.5% bupivacaine 20 mL provided faster onset of complete conduction blockade during ultrasound-guided supraclavicular brachial plexus block than 20 mL of 0.5% bupivacaine alone: a randomized double-blinded clinical trial. Reg Anesth Pain Med. Published 9 June 2023. doi:10.
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