The ED95 of lidocaine and prilocaine for ultrasound-guided brachial plexus blocks for surgical anaesthesia: a randomised controlled clinical trial
Authors' conclusion
We achieved a 95% success rate for axillary blocks using lidocaine (1% and 2%) with adrenaline within our dosing limits.
Study context
- Population
- Patients receiving ultrasound-guided axillary or supraclavicular brachial plexus blocks for surgical anaesthesia
- Participants
- 41 / 40 / 31 / 42
- Comparison
- Lidocaine 1% vs 2% with adrenaline (axillary); prilocaine 1% vs lidocaine 1% with adrenaline (supraclavicular)
- An = 41
- Bn = 40
- Cn = 31
- Dn = 42
- Primary endpoint
- Loss of cold and pin-prick sensations in median, musculocutaneous, radial and ulnar nerve distributions
Methodological detailsdouble-blind, prospective, dose-finding, modified continual reassessment method
- Double-blind
- Prospective
- Dose-finding
- Modified continual reassessment method
Primary result
As reported in the abstract
ED95
Original publication
The ED95 of lidocaine and prilocaine for ultrasound-guided brachial plexus blocks for surgical anaesthesia: a randomised controlled clinical trial. BJA Open. Published 14 March 2025. doi:10.
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