Erector spinae plane block versus quadratus lumborum block for postoperative analgesia after laparoscopic nephrectomy: A randomized controlled trial
Primary result · Cumulative sufentanil equivalentResult — go to the resultMedian difference - 8 μg 95% CI −15 to 0Authors' conclusion
Compared with quadratus lumborum block, erector spinae plane block provided better analgesia as manifested by lower opioid consumption and pain intensity for up to 24 h after laparoscopic nephrectomy.
Study context
- Population
- Patients scheduled for elective laparoscopic nephrectomy, tertiary hospital in Beijing, Chinaall in ITT analysis
- Participants
- 110 patients
- Comparison
- ESP block vs QL block
- ESP blockn = 55
- QL blockn = 55reference
- Primary endpoint
- Cumulative opioid (sufentanil equivalent) consumption
- Follow-up
- 24 h after surgery
Methodological detailsultrasound-guided, single-centre
- Ultrasound-guided
- Single-centre
Primary result
Cumulative sufentanil equivalent · up to 24 h
Median difference
- 8 μg
95% CI −15 to 0
P = 0.041
By group
ESP block vs QL block
median difference - 8 μg (95% CI −15 to 0); P = 0.041
As reported in the abstract
Secondary outcomes
| Outcome | Median difference (95% CI) | P value | |
|---|---|---|---|
| Subjective sleep quality (Richards-Campbell Sleep Questionnaire, 0-100, higher better) · night of surgery | 12 (2–23) | P = 0.018 | |
| Quality of recovery (QoR-15, 0-150, higher better) · up to 24 h | 8 (2–15) | P = 0.012 | |
| −100102030Difference (linear scale) |
| Outcome | Estimate | P value |
|---|---|---|
| Pain intensity at rest (0-10) · 2, 6, 12, and 24 h | median difference −1 point | all P ≤ 0.009 |
| Pain intensity with movement (0-10) · 2, 6, 12, and 24 h | median differences −2 to −1 points | all P < 0.001 |
Safety
Events
| Outcome | ESP block | QL block |
|---|---|---|
| Procedure-related adverse events | 0 | 0 |
Original publication
Erector spinae plane block versus quadratus lumborum block for postoperative analgesia after laparoscopic nephrectomy: A randomized controlled trial. J Clin Anesth. Published 26 April 2024. doi:10.
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