Cardiothoracic & vascular anesthesia
Evaluation of Intraoperative Left-Ventricular Diastolic Function by Myocardial Strain in On-Pump Coronary Artery Bypass Surgery
Authors' conclusion
Intraoperative assessment of strain-based measurements of LV diastolic function and strain-based LVDD grading was feasible in this group of selected patients, whereas conventional parameters failed to describe LVDD sufficiently in a substantial number of patients. Diastolic strain-based measurements showed impairment of LV relaxation and compliance after bypass, which was not detected by conventional echocardiographic parameters.
Study context
- Population
- Adults scheduled for isolated on-pump CABG with preserved left and right ventricular systolic function, without significant valve disease or pulmonary hypertension, and an uneventful intraoperative course
- Participants
- 30 adults
- Exposure
- Strain-based vs conventional transesophageal echocardiography (TEE) assessment of left ventricular (LV) diastolic function at T1 (after induction), T2 (after CPB) and T3 (after sternal closure)
- Outcome
- Feasibility of LV diastolic function grading
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Conventional grading indeterminate, T1
40%
Conventional grading indeterminate, T2
33%
Conventional grading indeterminate, T3
36%
Observational data: associations, not effects.
Further findings
| Outcome | T1 | T2 | P value |
|---|---|---|---|
| SR-IVRT2 vs T1 | 0.28 (IQR 0.23–0.31) s-1 | 0.18 (IQR 0.14–0.22) s-1 | P < 0.001 |
| SR-ET2 vs T1 | 0.95 ± 0.34 s-1 | 1.28 ± 0.36 s-1 | P < 0.001 |
| E/SR-IVRT2 vs T1 | 2.3 ± 1.0 m | 4.5 ± 2.1 m | P < 0.001 |
| E/AT2 vs T1 | 1.27 (IQR 0.94–1.59) | 1.21 (IQR 1.03–1.47) | P = 1 |
| E/e´T2 vs T1 | 7.0 (IQR 5.3–9.6) | 6.35 (IQR 5.7–9.9) | P = 0.9 |
Before vs after sternal closure (T2 vs T3)
- No significant changes in SR-IVR, SR-E, SR-A, E/SR-IVR, E/A and E/e´
Original publication
Composed by AI from the published abstract and checked against it. How Briefs are made →