Cardiothoracic & vascular anesthesia
Intraoperative Assessment of Noninvasive Left Ventricular Myocardial Work Indices in Patients Undergoing Aortic Valve Replacement
Authors' conclusion
LV MW analysis showed a reduction of LV workload after bypass in our group of patients, which was not detected by conventional echocardiographic measures.
Study context
- Population
- Patients scheduled for isolated aortic valve replacement (AVR) with preoperative preserved left and right ventricular function, sinus rhythm, no significant other valve disease or pulmonary hypertension, and an uneventful intraoperative course
- Participants
- 25 patients
- Exposure
- Left ventricular (LV) myocardial work indices vs conventional 2D/3D echocardiography and strain, across intraoperative time points
- Outcome
- LV myocardial work indices (TOE)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- Estimation of myocardial work feasible in all patients
- No significant difference in 2D and 3D ejection fraction (EF)
- No significant change in global work index (GWI), global constructive work (GCW), or 2D and 3D LVEF before and after sternal closure (T2 v T3)
- T2 vs T1: P < 0.001
- T2 vs T1: P < 0.001
- T2 vs T1: P = 0.97
- T2 vs T1: P < 0.001
- T3 vs T2: P = 0.003
Observational data: associations, not effects.
Original publication
Intraoperative Assessment of Noninvasive Left Ventricular Myocardial Work Indices in Patients Undergoing Aortic Valve Replacement. J Cardiothorac Vasc Anesth. Published 6 July 2024. doi:10.
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