Cardiothoracic & vascular anesthesia

Evaluation of Mitral-Aortic Flow Velocity Integral Ratio as a Tool to Differentiate Between Severe and Nonsevere Mitral Regurgitation

J Cardiothorac Vasc AnesthPublished Diagnostic accuracy study

Authors' conclusion

MAVIR may be used as an echocardiographic tool to differentiate between severe and nonsevere MR, even in patients with calcific valves.

Study context

Population
Adults with chronic mitral regurgitation (MR) (at least mild) scheduled for cardiac surgery, without mitral stenosis, aortic valve disease or non-sinus rhythm; tertiary-care cardiac OR24 with calcific mitral valve
Participants
100 adults
Comparison
MAVIR vs regurgitant volume (RVol) and effective regurgitant orifice area (EROA) for differentiating severe from nonsevere MR, by TTE and transesophageal (TEE)
Outcome
Agreement (Cohen's kappa) of MAVIR with RVol and EROA in differentiating severe from nonsevere MR, by TTE and TEE
Methodological detailsprospective, cross-sectional, observational, single-centre
  • Prospective
  • Cross-sectional
  • Observational
  • Single-centre

Performance

As reported in the abstract

Agreement in differentiating severe from nonsevere MR
  • Strong agreement between MAVIR and both RVol and EROA in the whole cohort, by TTE and TEE

Further findings

Agreement in calcific mitral valve (subgroup)

Strong agreement between MAVIR and both RVol and EROA, by TTE and TEE
  • n = 24

Diagnostic indices of MAVIR for severe MR

Diagnostic indices high for MAVIR compared with RVol and EROA, by TTE and TEE

Original publication

Evaluation of Mitral-Aortic Flow Velocity Integral Ratio as a Tool to Differentiate Between Severe and Nonsevere Mitral Regurgitation. J Cardiothorac Vasc Anesth. Published 9 October 2022. doi:10.1053/j.jvca.2022.10.002

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