Pain medicine

Evaluation of neuraxial analgesia on outcomes for patients undergoing robot assisted abdominal surgery

J Clin AnesthPublished Systematic review and meta-analysis of randomised trials and observational studies

Pooled result · Coprimary outcomes, spinal analgesia with long acting neuraxial opioid (meta-analysis of RCTs)Result — go to the resultMD 14.88 mg 95% CI −22.13--7.63

Authors' conclusion

Spinal analgesia with long acting neuraxial opioid had a favourable effect on analgesic indices and opioid consumption, and is recommended by the authors, but the evidence for spinal analgesia with short acting neuraxial opioid and epidural analgesia was limited.

Study context

Population
Adults undergoing robot assisted abdominal surgery19 spinal, 11 epidural studies
Comparison
Neuraxial analgesia vs control
Outcome
Coprimary: pain score at rest and cumulative IV morphine consumption
Follow-up
24 h
Methodological detailsdescriptive synthesis of studies not meta-analysed
  • Descriptive synthesis of studies not meta-analysed

Pooled result

As reported in the abstract

Coprimary outcomes, spinal analgesia with long acting neuraxial opioid (meta-analysis of RCTs)

MD

14.88 mg

95% CI −22.13--7.63

P < 0.0001

Further pooled results

Analgesic indices and opioid consumption over time (spinal)

Beneficial effect on analgesic indices till second postoperative day and on opioid consumption up to and including 72 h

QoR-15 at 24 h and hospital LOS (spinal)

Evidence not fully consistent; most studies no difference vs control

Pain on movement (epidural)

Decreased at 12 h; not reduced at later time points

Hospital LOS (epidural)

Evidence inconsistent

Original publication

Evaluation of neuraxial analgesia on outcomes for patients undergoing robot assisted abdominal surgery. J Clin Anesth. Published 9 April 2024. doi:10.1016/j.jclinane.2024.111468

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