Evaluation of neuraxial analgesia on outcomes for patients undergoing robot assisted abdominal surgery
Pooled result · Coprimary outcomes, spinal analgesia with long acting neuraxial opioid (meta-analysis of RCTs)Result — go to the resultMD 14.88 mg 95% CI −22.13--7.63Authors' conclusion
Spinal analgesia with long acting neuraxial opioid had a favourable effect on analgesic indices and opioid consumption, and is recommended by the authors, but the evidence for spinal analgesia with short acting neuraxial opioid and epidural analgesia was limited.
Study context
- Population
- Adults undergoing robot assisted abdominal surgery19 spinal, 11 epidural studies
- Comparison
- Neuraxial analgesia vs control
- Outcome
- Coprimary: pain score at rest and cumulative IV morphine consumption
- Follow-up
- 24 h
Methodological detailsdescriptive synthesis of studies not meta-analysed
- Descriptive synthesis of studies not meta-analysed
Pooled result
As reported in the abstract
Coprimary outcomes, spinal analgesia with long acting neuraxial opioid (meta-analysis of RCTs)
MD
14.88 mg
95% CI −22.13--7.63
P < 0.0001
Further pooled results
Analgesic indices and opioid consumption over time (spinal)
- Beneficial effect on analgesic indices till second postoperative day and on opioid consumption up to and including 72 h
QoR-15 at 24 h and hospital LOS (spinal)
- Evidence not fully consistent; most studies no difference vs control
Pain on movement (epidural)
- Decreased at 12 h; not reduced at later time points
Hospital LOS (epidural)
- Evidence inconsistent
Original publication
Evaluation of neuraxial analgesia on outcomes for patients undergoing robot assisted abdominal surgery. J Clin Anesth. Published 9 April 2024. doi:10. 1016/ j. jclinane. 2024. 111468
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