Extracorporeal Blood Purification with CytoSorb in Patients with Shock: A Secondary Analysis of Standalone Circuit Configuration Versus Integrated Use within Extracorporeal Membrane Oxygenation in 359 Critically Ill Patients
Authors' conclusion
Despite substantial intergroup diversity at baseline and in their clinical outcomes, the choice of CytoSorb configuration had no impact on cartridge performance and duration.
Study context
- Population
- Critically ill patients receiving CytoSorb, cardiac ICU of a tertiary referral university hospital
- Participants
- 359 patients
- Comparison
- Standalone vs extracorporeal membrane oxygenation (ECMO)
- Standalonen = 148
- ECMOn = 211reference
Methodological detailssingle-centre
- Single-centre
Primary result
As reported in the abstract
Cartridge performance and duration
- Median of two CytoSorb cartridges per cycle across both groups
- two
Further findings
ICU survival
P < 0.001
Hospital survival
P < 0.001
| Outcome | P value |
|---|---|
| RRT useSignificantly greater use with ECMO | P < 0.001 |
RRT use
- RRT in up to 34% of overall population
Original publication
Extracorporeal Blood Purification with CytoSorb in Patients with Shock: A Secondary Analysis of Standalone Circuit Configuration Versus Integrated Use within Extracorporeal Membrane Oxygenation in 359 Critically Ill Patients. J Cardiothorac Vasc Anesth. Published 3 September 2025. doi:10.
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