Cardiac arrest & resuscitation

Extracorporeal Versus Conventional Cardiopulmonary Resuscitation for In-Hospital Cardiac Arrest: A Propensity Score Matching Cohort Study

Crit Care MedPublished Retrospective cohort study

Authors' conclusion

ECPR may be beneficial compared with CCPR for patient survival after IHCA

Study context

Population
Patients with in-hospital cardiac arrest (IHCA) receiving CPR without contraindications to ECPR, aged ≤75 yr, witnessed, CPR duration ≥10 min; BASIC-IHCA study, 39 hospitals in China, July 2019–December 2020before matching
Participants
4,853 patients
Exposure
ECPR vs conventional cardiopulmonary resuscitation (CCPR)
  • ECPRn = 33
  • CCPRn = 132reference
Outcome
Survival to discharge or 30-day survival
Methodological detailspropensity-score matched (1:4), multicentre registry
  • Propensity-score matched (1:4)
  • Multicentre registry

Main finding

As reported in the abstract

P = 0.048

Observational data: associations, not effects.

Further findings

OutcomeHR (95% CI)
Mortality at discharge or 30 days0.57 (0.38–0.91)

Survival rate of ECPR patients in participating hospitals (questionnaire survey, January–November 2021)

Survival rate of patients with ECPR significantly improved (29.4% vs. 10.4%)
P = 0.004

Original publication

Extracorporeal Versus Conventional Cardiopulmonary Resuscitation for In-Hospital Cardiac Arrest: A Propensity Score Matching Cohort Study. Crit Care Med. Published 5 March 2024. doi:10.1097/ccm.0000000000006223

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