Cardiothoracic & vascular anesthesia
Factors Influencing Operating Room Extubation of Adults With Congenital Heart Disease Undergoing Cardiac Surgery: A Single-Center Experience
Authors' conclusion
Operative time in minutes had the strongest correlation with clinicians' decision to return to the ICU intubated. In this cohort of patients, the contribution of BMI to the decision not to extubate in the OR was clinically and statistically insignificant.
Study context
- Population
- Adults with congenital heart disease (ACHDs) undergoing cardiac surgery, single pediatric congenital heart disease program within a quaternary care center, August 2018–December 2025
- Participants
- 172 adults
- Exposure
- OR extubation vs extubation in the intensive care unit (ICU)
- Extubated in the ORn = 112
- Extubated in the ICUn = 60reference
- Outcome
- Factors associated with extubation after transfer to the ICU (multivariate)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- CPB time (min), marker for operative length, final model: aOR
- 0.99
- CPB time P
- p < 0.0001
- Body mass index (BMI) not associated with extubation in the OR: aOR
- 0.94
- BMI P
- p = 0.056
Observational data: associations, not effects.
Further findings
BMI (univariate)
P = 0.259
| Outcome | Estimate | P value |
|---|---|---|
| Hospital LOSShorter; not significant after multivariate regression | β 7.04 | P = 0.103 |
| 30-day readmission · not significant after multivariate regression | OR 0.34 | P = 0.122 |
Safety
- Reintubation — Extubated in the OR
- 0.58% (95% CI 0.01%–3.2%)
- Reintubation: Overall 2.3% (95% CI 0.01%–3.2%)
- Reintubation: denominator 172 as printed for both
Original publication
Factors Influencing Operating Room Extubation of Adults With Congenital Heart Disease Undergoing Cardiac Surgery: A Single-Center Experience. J Cardiothorac Vasc Anesth. Published 21 April 2026. doi:10.
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