ICU sedation, delirium & recovery

Frailty and one year survival in patients admitted to the intensive care unit following a medical emergency team review: a retrospective registry-based study

ResuscitationPublished Retrospective registry-based cohort study

Authors' conclusion

In this large cohort of ICU patients admitted after a MET review, frailty was independently associated with higher one-year mortality, with outcomes worsening progressively with incrementing CFS.

Study context

Population
Adults (≥16 years) admitted to 184 intensive care unit (ICUs) after a ward medical emergency team (MET) review, 1 January 2018–30 June 2022, with a documented Clinical Frailty Scale (CFS) score (ANZICS Adult Patient Database)
Participants
48,425 adults · 184 ICUs
Exposure
Clinical Frailty Scale categories 2–8 vs CFS-1
Outcome
One-year mortality
Follow-up
One year
Methodological detailsmultivariable hierarchical logistic regression, linkage with national death registries
  • Multivariable hierarchical logistic regression
  • Linkage with national death registries

Main finding

As reported in the abstract

One-year mortality (adjusted)

Adjusted attributable mortality risk

+5.6%

95% CI 2.8–8.4%

CFS-2

Adjusted attributable mortality risk

+48.5%

95% CI 43.6–53.4%

CFS-8

Observational data: associations, not effects.

Original publication

Frailty and one year survival in patients admitted to the intensive care unit following a medical emergency team review: a retrospective registry-based study. Resuscitation. Published 4 February 2026. doi:10.1016/j.resuscitation.2026.110995

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