Cardiothoracic & vascular anesthesia

Functional intervention following cardiac surgery to prevent postoperative delirium in older patients (FEEL WELL study)

J Intensive CarePublished Randomised controlled trial

Authors' conclusion

Results of the study imply that a multisensory stimulation done on the first 3 days after planned cardiac surgery can reduce the incidence and duration of postoperative delirium in older patients.

Study context

Population
Patients over 65 years with elective cardiac surgery, University Hospital Bonn, Germany, 2021–2022
Participants
186 participants
Comparison
Multisensory stimulation vs control
Primary endpoint
Incidence of postoperative delirium (3-min diagnostic interview for CAM)
Follow-up
First 5 days after surgery
Methodological detailsprospective, non-pharmacological intervention, single-centre
  • Prospective
  • Non-pharmacological intervention
  • Single-centre

Primary result

As reported in the abstract

Incidence of postoperative delirium

P < 0.001

Further findings

OutcomeP value
Duration of postoperative deliriumP < 0.001
ICU stayP = 0.006

Duration of postoperative delirium

Significantly shorter in the intervention group

ICU stay

Significantly longer in the control group

Factors associated with postoperative delirium (regression model)

Non-intervention
P = 0.007
High pain scores
P = 0.032
Advanced age
P = 0.006
Prolonged mechanical ventilation
P = 0.006

Original publication

Functional intervention following cardiac surgery to prevent postoperative delirium in older patients (FEEL WELL study). J Intensive Care. Published 13 December 2023. doi:10.1186/s40560-023-00711-1

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