Respiratory failure & ventilation

Functional recovery in a cohort of ECMO and non-ECMO acute respiratory distress syndrome survivors

Crit CarePublished Retrospective cohort study

Authors' conclusion

There were no significant differences in the FVC% predicted, or other markers of pulmonary, neurocognitive, or psychiatric functional recovery outcomes, when comparing a contemporaneous clinic-based cohort of survivors of ARDS managed with ECMO to those without ECMO.

Study context

Population
ARDS survivors who presented to follow-up clinic
Participants
110 survivors
Exposure
ECMO vs non-ECMO management
  • ECMOn = 34
Outcome
FVC% predicted
Methodological detailsmulticentre, Univariate and multivariate regression models
  • Multicentre
  • Univariate and multivariate regression models

Main finding

As reported in the abstract

  • No significant difference in FVC% predicted between ECMO and non-ECMO
  • ECMO did not predict changes in lung function adjusting for age, Sequential Organ Failure Assessment (SOFA), COVID-19 status or LOS

Observational data: associations, not effects.

Further findings

Hospital LOS

P < 0.01

ICU stay

P < 0.01

Duration of mechanical ventilation

P < 0.01

Other pulmonary, neurocognitive and psychiatric functional outcomes

Similar in ECMO and non-ECMO

Original publication

Functional recovery in a cohort of ECMO and non-ECMO acute respiratory distress syndrome survivors. Crit Care. Published 14 November 2023. doi:10.1186/s13054-023-04724-y

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.