Cardiothoracic & vascular anesthesia

Gender is Independently Associated With Red Blood Cell and Platelet Transfusion in Patients Undergoing Coronary Artery Bypass Grafting: Data From the Netherlands Heart Registration

J Cardiothorac Vasc AnesthPublished Retrospective cohort study

Authors' conclusion

The incidence of any blood transfusion was 27.0%, and was higher in women than in men. The female sex was independently associated with receiving RBC during and after CABG.

Study context

Population
Adults >18 years undergoing coronary artery bypass grafting (CABG) (on- or off-pump), Netherlands Heart Registration, 16 heart centres, 2013–2021
Participants
42,388 adults
Exposure
Women vs men
Outcome
Incidence of blood transfusion (intraoperative and during hospital admission after CABG), by type (RBC, platelets, FFP)
Methodological detailsmulticentre, registry
  • Multicentre
  • Registry

Main finding

As reported in the abstract

Any transfusion (overall cohort)

Patients receiving a transfusion of any type

27.0%

n = 11,428

Observational data: associations, not effects.

Further findings

RBC transfusion

P < 0.001

Platelet transfusion

P = 0.005

Red blood cells (RBC) transfusion

Female sex independently associated with RBC transfusion (multivariate logistic regression)

Fresh frozen plasma (FFP) transfusion

No significant difference between sexes

Original publication

Gender is Independently Associated With Red Blood Cell and Platelet Transfusion in Patients Undergoing Coronary Artery Bypass Grafting: Data From the Netherlands Heart Registration. J Cardiothorac Vasc Anesth. Published 27 December 2023. doi:10.1053/j.jvca.2023.12.033

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