Cardiac arrest & resuscitation
Gender-related differences in adults concerning frequency, survival and treatment quality after out-of-hospital cardiac arrest (OHCA): An observational cohort study from the German resuscitation registry
Authors' conclusion
In Germany, 80% more men than women experience OHCA. The prognosis for CPC1/2discharge remains low (men = 10.5%, women = 7.1%), but comparable after risk adjustment.
Study context
- Population
- Adults ≥18 years with OHCA and resuscitation, German Resuscitation Registry 2006–202227,910 admitted
- Participants
- 58,798 adults
- Exposure
- Men vs women
- Outcome
- Risk-adjusted ROSC at hospital admission (all patients) and discharge with favourable neurological recovery (CPC 1/2; admitted patients)
Methodological detailsregistry-based, risk-adjusted (logistic regression), matched-pairs analysis
- Registry-based
- Risk-adjusted (logistic regression)
- Matched-pairs analysis
Main finding
As reported in the abstract
ROSC at hospital admission (all patients); CPC 1/2 at discharge (admitted patients)
Men
10.5%
CPC1/2 at discharge
Women
7.1%
CPC1/2 at discharge
Men vs WomenOdds ratio (CI)
Hospital care (admitted patients, n = 27,910)
1.10(1.015–1.191)
CPC1/2 at discharge, complete chain of survival (n = 58,798); risk-adjusted (LRA), no difference
0.95(0.888–1.024)
Observational data: associations, not effects.
Further findings
Intensity of therapy (matched-pairs analysis)
- More intensive therapy for men during both EMS and hospital care
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Gender-related differences in adults concerning frequency, survival and treatment quality after out-of-hospital cardiac arrest (OHCA): An observational cohort study from the German resuscitation registry. Resuscitation. Published 25 November 2023. doi:10.
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