Glucagon-like peptide-1 receptor agonists and retained gastric contents on endoscopy: a prospective observational study
Authors' conclusion
In this small observational study, no statistically significant increase in RGC was noted when preprocedural instructions advised patients to hold GLP-1 RAs 1 week prior to endoscopy and follow a preprocedural 24-hr clear liquid diet.
Study context
- Population
- Patients scheduled for elective endoscopy involving stomach visualization
- Participants
- 256 patients
- Exposure
- GLP-1 RA users vs controls
- Outcome
- Retained gastric contents (solid content or liquid-only content > 1.5 mL·kg-1 body weight)
Main finding
As reported in the abstract
Incidence of retained gastric contents (RGC)
P = 0.55
Observational data: associations, not effects.
Secondary outcomes
Endoscopy physician-reported concern of significant gastric contents
Safety
- No occurrences of aspiration events, procedure abortion, or relevant conversion to GA
Original publication
Glucagon-like peptide-1 receptor agonists and retained gastric contents on endoscopy: a prospective observational study. Can J Anaesth. Published 19 August 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →