Healthcare costs after sepsis: a systematic review
Authors' conclusion
Our systematic review demonstrates that sepsis survivors incur high healthcare costs that can persist for years after discharge from initial hospitalization.
Study context
- Population
- Adults in developed nations who survived an episode of sepsis23 observational studies
- Outcome
- Post-hospitalization healthcare costs
Methodological detailsnarrative synthesis, Newcastle-Ottawa quality assessment
- Narrative synthesis
- Newcastle-Ottawa quality assessment
Pooled result
As reported in the abstract
Total healthcare cost after discharge
Median total healthcare cost, year one after discharge (IQR $21,715)
$28,719
Median total healthcare cost, year two after discharge (IQR $14,407)
$22,460
Further pooled results
| Outcome | Values |
|---|---|
| Cost of a readmission | Sepsis survivors median $20,320 (IQR $4,889) |
Costs vs non-sepsis comparator
- Studies with a non-sepsis comparator reporting higher post-discharge costs in sepsis survivors
- 6 of 7
Original publication
Healthcare costs after sepsis: a systematic review. Crit Care. Published 22 August 2025. doi:10. 1186/ s13054-025-05600-7
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