Sepsis & infection

Healthcare costs after sepsis: a systematic review

Crit CarePublished Systematic review

Authors' conclusion

Our systematic review demonstrates that sepsis survivors incur high healthcare costs that can persist for years after discharge from initial hospitalization.

Study context

Population
Adults in developed nations who survived an episode of sepsis23 observational studies
Outcome
Post-hospitalization healthcare costs
Methodological detailsnarrative synthesis, Newcastle-Ottawa quality assessment
  • Narrative synthesis
  • Newcastle-Ottawa quality assessment

Pooled result

As reported in the abstract

Total healthcare cost after discharge

Median total healthcare cost, year one after discharge (IQR $21,715)

$28,719

Median total healthcare cost, year two after discharge (IQR $14,407)

$22,460

Further pooled results

OutcomeValues
Cost of a readmissionSepsis survivors median $20,320 (IQR $4,889)

Costs vs non-sepsis comparator

Studies with a non-sepsis comparator reporting higher post-discharge costs in sepsis survivors
6 of 7

Original publication

Healthcare costs after sepsis: a systematic review. Crit Care. Published 22 August 2025. doi:10.1186/s13054-025-05600-7

Composed by AI from the published abstract and checked against it. How Briefs are made →

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