Organ support & nutrition

Heart rate variability as a marker of multiple organ dysfunction syndromes: a systematic review

J Clin Monit ComputPublished Systematic review

Authors' conclusion

The results of our review show that HRV indices are influenced by the severity of MODS and might serve as a tool for predicting mortality in patients with MODS.

Study context

Population
Patients of any age admitted to the ICU with multiple organ dysfunction syndrome (MODS)10 studies
Outcome
Value of HRV variables for the diagnosis of MODS
Methodological detailsQUADAS-2 quality assessment, PubMed, Embase, Cochrane and Science Direct searched, English or French, 2004–2024
  • QUADAS-2 quality assessment
  • PubMed, Embase, Cochrane and Science Direct searched, English or French, 2004–2024

Pooled result

As reported in the abstract

HRV in MODS and mortality
  • All studies showed low heart rate variability (HRV) in patients with MODS and in non-survivors
  • 9 studies assessed MODS, 6 assessed mortality

Original publication

Heart rate variability as a marker of multiple organ dysfunction syndromes: a systematic review. J Clin Monit Comput. Published 21 April 2025. doi:10.1007/s10877-025-01296-w

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