High-cost users after sepsis: a population-based observational cohort study
Main finding · Top 5% HCU for 90 consecutive daysResult — go to the resultOdds ratio 2.24 95% CI 2.04–2.46Authors' conclusion
After discharge, individuals who experienced sepsis are more likely to be a HCU and spend more time as a HCU compared to individuals who did not experience sepsis during hospitalization.
Study context
- Population
- Adults who survived a hospitalization in Ontario, Canada, January 2016–December 2017
- Participants
- 927,057 adults
- Exposure
- Sepsis vs no sepsis during hospitalization
- Sepsisn = 79,065
- Outcome
- Persistent high-cost users (HCU) after discharge (top 5% or 1% of total health care spending for 90 consecutive days), and proportion of follow-up time since discharge as a HCU
Methodological detailspropensity score-weighted, linked health-administrative databases
- Propensity score-weighted
- Linked health-administrative databases
Main finding
Top 5% HCU for 90 consecutive days
Odds ratio
2.24
95% CI 2.04–2.46
Sepsis vs Without sepsis
OR 2.24 (95% CI 2.04–2.46)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Sepsis | Without sepsis | Estimate | |
|---|---|---|---|---|
| Proportion of follow-up time as top 5% HCU | mean 42.3% | 28.9% | RR 1.46 (95% CI 1.45–1.48) | |
| Top 1% HCU for 90 consecutive days | 10% | 5.1% | OR 2.05 (95% CI 1.99–2.11) | |
| Proportion of follow-up time as top 1% HCU | 18.5% | 10.8% | RR 1.68 (95% CI 1.65–1.70) | |
| 0.512Ratio (log scale) |
Original publication
High-cost users after sepsis: a population-based observational cohort study. Crit Care. Published 21 October 2024. doi:10.
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