High-density lipoprotein: a biomarker and therapeutic target in sepsis
Study context
- Population
- Sepsis
Main finding
As reported in the abstract
- Sepsis substantially decreases high-density lipoprotein (HDL) in experimental and clinical studies
- High HDL level associated with better sepsis-related prognosis
- HDL protective functions: endotoxin-neutralizing, anti-bacterial, anti-inflammatory, anti-oxidative
- Modulation of HDL as a potential therapeutic strategy in sepsis
Original publication
High-density lipoprotein: a biomarker and therapeutic target in sepsis. Crit Care. Published 27 October 2025. doi:10. 1186/ s13054-025-05702-2
Composed by AI from the published abstract and checked against it. How Briefs are made →