Respiratory failure & ventilation
High-flow nasal cannula and in-line aerosolised bronchodilator delivery during severe exacerbation of asthma in adults: a feasibility observational study
Authors' conclusion
HFNC treatment with in-line VMN for bronchodilator delivery appears feasible and safe for patients with severe asthma exacerbation.
Study context
- Population
- Adults ≥18 years with asthma admitted to the emergency department (ED) during severe exacerbationmostly female (67%)
- Participants
- 30 adults
- Exposure
- After treatment vs Before treatment
- Outcome
- Change in peak expiratory flow ratio (PEFR)
- Follow-up
- 2-h of treatment
Methodological detailspilot, single-group, May 2022 to May 2023
- Pilot
- Single-group
- May 2022 to May 2023
Main finding
As reported in the abstract
PEFR
P < 0.001
Observational data: associations, not effects.
Further findings
- Significant improvement in clinical variables after treatment
Safety
Invasive mechanical ventilation
- No subjects required invasive mechanical ventilation (IMV) during the study
Original publication
High-flow nasal cannula and in-line aerosolised bronchodilator delivery during severe exacerbation of asthma in adults: a feasibility observational study. Anaesth Crit Care Pain Med. Published 30 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →