Pediatric anesthesia & critical care
High-Frequency Low–Tidal Volume Ventilation and Catheter–Tissue Interaction During Pediatric Radiofrequency Ablation: A Prospective Observational Study
Authors' conclusion
This prospective observational study found that different ventilation strategies influenced catheter-tissue interaction and procedural metrics during pediatric RF ablation. Notably, HFLTV ventilation was linked to higher contact force metrics.
Study context
- Population
- Patients aged < 18 years undergoing cardiac radiofrequency (RF) ablation for supraventricular tachycardia, tertiary pediatric electrophysiology center, June–September 2025
- Participants
- 133 consecutive patients
- Exposure
- High-frequency low-tidal volume (HFLTV) ventilation vs standard ventilation vs controlled apnea
- HFLTVn = 65
- Standard ventilation (SV)n = 32reference
- Controlled apnean = 36
- Outcome
- Mean contact force (MCF)
Methodological detailssingle-centre, consecutive patients, Ventilation strategy chosen by attending anesthesiologist per routine practice; investigators had no role
- Single-centre
- Consecutive patients
- Ventilation strategy chosen by attending anesthesiologist per routine practice; investigators had no role
Main finding
As reported in the abstract
Mean contact force
HFLTV vs SV: P < 0.001 · HFLTV vs Controlled apnea: P < 0.001
Observational data: associations, not effects.
Secondary outcomes
Mean
| Outcome | HFLTV | SV | Controlled apnea | P value |
|---|---|---|---|---|
| Operator-rated procedural quality score (PQS, scale 1-10)HFLTV vs SV · statistic and spread not named in abstract; printed as ± | 8.1 (SD 1.0) | 7.0 (SD 2.0) | 7.1 (SD 1.0) | P < 0.001 |
| Operator-rated procedural quality score (PQS, scale 1-10)HFLTV vs Controlled apnea · statistic and spread not named in abstract; printed as ± | P < 0.001 |
Minimum and mean impedance
- Lower in the HFLTV group
RF time and overall procedure duration
- Similar across the groups
Safety
- No ventilation-related complications observed
Original publication
High-Frequency Low–Tidal Volume Ventilation and Catheter–Tissue Interaction During Pediatric Radiofrequency Ablation: A Prospective Observational Study. J Cardiothorac Vasc Anesth. Published 18 March 2026. doi:10.
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