Cardiothoracic & vascular anesthesia
High Postreperfusion Pulmonary Artery Pressure Is Associated With Increased 30-Day Mortality in Liver Transplantation
Main finding · Association of elevated postreperfusion mPAP with 30-day mortalityResult — go to the resultOdds ratio 6.056 95% CI 2.349–15.611Authors' conclusion
This retrospective study found a 7.3% rate of high PAP following reperfusion in LT, and high postreperfusion PAP was associated with 30-day mortality.
Study context
- Population
- Consecutive adults undergoing liver transplantation at a university tertiary centre, 2013–2023
- Participants
- 1,243 adults
- Exposure
- Elevated vs non-elevated postreperfusion mean pulmonary artery pressure (mPAP)
- Elevated mPAPn = 91
- Outcome
- Association of elevated postreperfusion mPAP with 30-day mortality
- Follow-up
- 30 days
Methodological detailssingle-centre, consecutive patients
- Single-centre
- Consecutive patients
Main finding
As reported in the abstract
Odds ratio
6.056
95% CI 2.349–15.611
P < 0.001
Elevated mPAP vs Non-elevated mPAP
OR 6.056 (95% CI 2.349–15.611); P < 0.001
Observational data: associations, not effects.
Further findings
- Incidence of elevated postreperfusion mPAP · first hour after reperfusion — Elevated mPAP
- 7.3%
Risk factors for elevated postreperfusion mPAP (multivariable logistic regression)
- Preoperative elevated PAP on echocardiogram, preoperative serum creatinine and intraoperative epinephrine use were significant risk factors
30-day mortality, whole cohort
- Died within 30 days after liver transplantation (LT)
- 32 (1.9%)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
High Postreperfusion Pulmonary Artery Pressure Is Associated With Increased 30-Day Mortality in Liver Transplantation. J Cardiothorac Vasc Anesth. Published 4 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →