Cardiothoracic & vascular anesthesia
Impact of graft reperfusion on cardiac function assessed by transesophageal echocardiography during liver transplantation: an observational retrospective study
Authors' conclusion
Liver graft reperfusion may alter cardiac function. Cardiac dysfunction was more frequent in patients with PRS. These patients exhibited temporary dysfunction of the RV associated with a varying degree of LV diastolic-systolic dysfunction.
Study context
- Population
- Patients undergoing orthotopic liver transplantation monitored with transesophageal echocardiography (TEE)
- Participants
- 34 patients
- Exposure
- Patients with postreperfusion syndrome (PRS) vs without PRS
- Outcome
- Cardiac dysfunction (TEE parameters of ventricular function)
- Follow-up
- 1 and 30 min after vascular unclamping
Main finding
As reported in the abstract
Cardiac dysfunction 1 min after vascular unclamping · 1 min after unclamping
- RV dilation incidence 4.5 times greater in PRS (Cramer´s V > 0.6)
- RV systolic dysfunction: PRS 62.5% vs non-PRS 15.40% (Cramer´s V = 0.45)
- LV systolic dysfunction: PRS 25% vs non-PRS 0% (Cramer´s V = 0.45)
- LV diastolic dysfunction 4.8 times greater in PRS (Cramer´s V = 0.45)
- No patient presented diastolic dysfunction type III
- No systolic/diastolic dysfunction on basal echocardiogram
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Evolutionary pattern at 1 and 30 min after unclampingPRS vs non-PRS · general linear model-repeated measures | P = 0.008 |
| Evolutionary pattern at 1 and 30 min after unclampingPRS vs non-PRS · general linear model-repeated measures | P = 0.014 |
Original publication
Impact of graft reperfusion on cardiac function assessed by transesophageal echocardiography during liver transplantation: an observational retrospective study. J Clin Monit Comput. Published 30 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →