Cardiothoracic & vascular anaesthesia
Intraoperative Right Ventricular Systolic Function in Liver Transplantation Recipients: A Prospective Observational Study Using Transesophageal Echocardiography During Living-Donor Liver Transplantation
Authors' conclusion
Transient reductions in RV systolic indices occurred predominantly during inferior vena cava clamping and improved following reperfusion.
Study context
- Population
- Adults undergoing living-donor liver transplantation (LDLT)38 (76%) men
- Participants
- 50 adults
- Outcome
- Time-dependent change in RV systolic indices (TAPSE, RVFAC, tissue Doppler S' velocity) on intraoperative transesophageal echocardiography (TEE)
- Follow-up
- 5 predefined surgical phases
Methodological detailsphysiological echocardiographic, single tertiary transplant centre, Median Model for End-Stage Liver Disease score 16 (IQR 9)
- Physiological echocardiographic
- Single tertiary transplant centre
- Median Model for End-Stage Liver Disease score 16 (IQR 9)
Main finding
As reported in the abstract
RV systolic indices across surgical phases
- Tricuspid annular plane systolic excursion (TAPSE), baseline
- 2.15 ± 0.31 cm
- TAPSE, inferior vena cava clamping
- 1.79 ± 0.45 cm
- TAPSE, end of surgery (p < 0.001)
- 2.08 ± 0.30 cm
- Tissue Doppler S' velocity, baseline → inferior vena cava clamping → end of surgery (p < 0.001)
- 10.58 ± 2.87 to 9.60 ± 2.89 to 11.72 ± 2.56 cm/s
- RV fractional area change (RVFAC) relatively preserved but varied significantly across time points
- p = 0.014
Observational data: associations, not effects.
Further findings
Left ventricular ejection fraction
- Remained stable
- P = 0.224
Hemodynamic variables
- Hemodynamic changes paralleled right ventricular (RV) alterations and responded to vasoactive support
Original publication
Intraoperative Right Ventricular Systolic Function in Liver Transplantation Recipients: A Prospective Observational Study Using Transesophageal Echocardiography During Living-Donor Liver Transplantation. J Cardiothorac Vasc Anesth. Published 19 August 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →