Respiratory failure & ventilation

High respiratory effort decreases splanchnic and peripheral perfusion in patients with respiratory failure during mechanical ventilation

J Crit CarePublished Prospective observational study

Authors' conclusion

HRE could decrease perfusion of peripheral tissues and splanchnic organs.

Study context

Population
Critically ill patients with respiratory failure during mechanical ventilationeach measured at high respiratory effort (HRE) and normal respiratory effort (NRE)
Participants
33 patients
Exposure
HRE vs NRE
Outcome
Peripheral and splanchnic perfusion (capillary refill time (CRT), peripheral perfusion index (PPI), Doppler resistance indices) from HRE to NRE

Main finding

As reported in the abstract

  • NRE vs HRE: P = 0.0345
  • NRE vs HRE: P < 0.0001
  • NRE vs HRE: P < 0.0001
  • NRE vs HRE: P = 0.0002
  • NRE vs HRE: P < 0.0001
  • NRE vs HRE: P < 0.0001

Observational data: associations, not effects.

Original publication

High respiratory effort decreases splanchnic and peripheral perfusion in patients with respiratory failure during mechanical ventilation. J Crit Care. Published 3 February 2023. doi:10.1016/j.jcrc.2023.154263

Composed by AI from the published abstract and checked against it. How Briefs are made →

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