Cardiothoracic & vascular anesthesia
Hypotension During Cardioplegia Administration: Does the Route of Delivery Matter?
Authors' conclusion
The incidence of intermittent vasoplegia during cardioplegia administration was significantly higher when delivered retrograde.
Study context
- Population
- Adult cardiac surgical patients requiring CPB, tertiary care academic medical center
- Participants
- 113 patients
- Exposure
- Retrograde vs antegrade subsequent cardioplegia administration
- Outcome
- Significant hypotension per cardioplegia administration
Methodological detailssingle-centre, automatically captured hemodynamic data from electronic perfusion record
- Single-centre
- Automatically captured hemodynamic data from electronic perfusion record
Main finding
As reported in the abstract
| Group | Value | Administrations |
|---|---|---|
| Retrograde | 35.8% | 246 |
| Antegrade | 22.2% | 99 |
Value
Retrograde35.8%
Antegrade22.2%
Administrations
Retrograde246
Antegrade99
- Retrograde vs Antegrade: P = 0.021
Observational data: associations, not effects.
Further findings
Patients with at least one 3 SD MAP decline (patient-level analysis)
P = 0.003
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Hypotension During Cardioplegia Administration: Does the Route of Delivery Matter? J Cardiothorac Vasc Anesth. Published 9 July 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →